Berenice, or Bernice, (Hebrew: ברניקי) was a daughter of Herod Agrippa I. She was a widow of Marcus Julius Alexander and then King Herod of Chalcis. With Herod of Chalcis, she was the mother of Berenicianus and Hyrcanus. After being widowed the second time, she married King Polemon II of Pontus, Colchis, and Cilicia but then she left him and resided with her brother Herod Agrippa II. She later became a mistress of Emperor Vespasian's son Titus.
Bernice was present when Paul was defending himself in front of Herod Agrippa II, as recounted in Acts 25–26.