Moses' Cushite wife
Moses' Cushite wife was a source of contention between the prophet Moses and his brother Aaron and his sister Miriam. Aaron and Miriam disapproved of Moses' marriage to a Cushite woman, and after they and the rest of the Israelites left Sinai, Miriam and Aaron expressed doubts about Moses' leadership due to this marriage. God then summoned Aaron and Miriam to the Tabernacle and chastened them for doubting Moses, who God trusted and spoke with directly.
God then cursed Miriam with leprosy. Moses pleaded with God to heal his sister, but God stated that disciplining her required seven days of shame, so Miriam was shunned for seven days. After the seven days passed, the curse was lifted, and Miriam was allowed to return.
Whether the Cushite woman was Zipporah or a different wife of Moses is not made clear in the Bible.